Prof. Dr. Sinan Ersin

1394 sokak No: 11 Sağlık Merkezi Apartmanı. Kat: 4 Daire: 10 Alsancak - İzmir


+90 (232) 464 67 68 - +90 (536) 355 27 66

What is GIST?


  • GIST (Gastro - Intestinal Stromal Tumor) is the most common mesenchymal tumor in the digestive system.
  • It is most common in the stomach. Most of the patients (90%) are over the age of forty.
  • Symptoms are usually related to the size of the tumor. There may be symptoms related to a vague abdominal pain and discomfort, weakness, anorexia and anemia. The tumor can sometimes bleed into the stomach and intestines or into the abdominal cavity.
  • If it settles in the esophagus, swallowing difficulties may also occur.
  • Endoscopic ultrasound is very useful in the diagnosis of those located in the stomach and esophagus. Standard treatment for GIST is surgical intervention. Most of the time, it is sufficient to remove a small area from the stomach together with the tumor. Generally, it is possible to completely remove the tumor.
  • Teamwork is important in maintaining treatment.
  • The most important part of determining the future risk of the disease and performing the follow-up of the patient is the microscopic examination of the tumor removed by surgery, that is, the pathology results. Low, medium or high risk grouping is made for the tumor by looking at some characteristics such as the diameter of the tumor and the rate of division of the cells within it.
  • In some cases, drug therapy is required in addition to surgical treatment.
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